Multilineage-differentiating Stress-enduring (Muse) Cell are a unique type of pluripotent stem cell, that hold immense promise for treating Alzheimer’s disease due to their remarkable regenerative and reparative capabilities. Unlike other stem cells, Muse cells can naturally home in on damaged brain tissue, differentiate into neural cells, and promote repair by replacing lost neurons and supporting neuroprotection. Their ability to modulate inflammation and integrate seamlessly into the host tissue without forming tumors makes them a safer and more effective option for restoring cognitive function. By harnessing Muse cells, we can potentially slow or reverse Alzheimer’s progression, offering hope for a groundbreaking therapy that addresses the disease’s root causes.